GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | cis | rs7267979 | 1 | rs4815406 | chr20:25341316 | ENTPD6 | chr20:25176339-25207360:+ | 0.32 | 7.24 | 1.84E-12 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815406 | chr20:25341316 | FAM182A | chr20:26035250-26067552:+ | 0.19 | 3.48 | 0.000539 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815406 | chr20:25341316 | FAM182B | chr20:25744102-25848786:- | -0.26 | -5.4 | 1.08E-7 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815406 | chr20:25341316 | NINL | chr20:25433338-25566153:- | 0.33 | 6.89 | 1.74E-11 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815406 | chr20:25341316 | PYGB | chr20:25228706-25278647:+ | 0.16 | 4.03 | 6.46E-5 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815407 | chr20:25341478 | ENTPD6 | chr20:25176339-25207360:+ | 0.3 | 6.7 | 5.92E-11 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815407 | chr20:25341478 | FAM182A | chr20:26035250-26067552:+ | 0.19 | 3.48 | 0.000553 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815407 | chr20:25341478 | FAM182B | chr20:25744102-25848786:- | -0.26 | -5.44 | 8.66E-8 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815407 | chr20:25341478 | NINL | chr20:25433338-25566153:- | 0.34 | 7.04 | 6.69E-12 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815407 | chr20:25341478 | PYGB | chr20:25228706-25278647:+ | 0.14 | 3.59 | 0.000359 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815408 | chr20:25346678 | ENTPD6 | chr20:25176339-25207360:+ | 0.3 | 6.84 | 2.39E-11 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815408 | chr20:25346678 | FAM182A | chr20:26035250-26067552:+ | 0.2 | 3.62 | 0.00032 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815408 | chr20:25346678 | FAM182B | chr20:25744102-25848786:- | -0.26 | -5.5 | 6.21E-8 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815408 | chr20:25346678 | NINL | chr20:25433338-25566153:- | 0.34 | 7.03 | 7.08E-12 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815408 | chr20:25346678 | PYGB | chr20:25228706-25278647:+ | 0.15 | 3.67 | 0.000274 | Liver enzyme levels (alkaline phosphatase) |